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Article

Validation study of HLA-B*13:01 as a biomarker of dapsone hypersensitivity syndrome in leprosy patients in Indonesia.

PLoS neglected tropical diseases - 1 Oct 2020

Krismawati Hana, Irwanto Astrid, Pongtiku Arry, Irwan Ishak Darryl, Maladan Yustinus, Sitanggang Yuli Arisanti, Wahyuni Tri, Tanjung Ratna, Sun Yonghu, Liu Hong, Zhang Furen, Oktavian Antonius, Liu Jianjun

Abstract excerpt

Leprosy is a stigmatizing, chronic infection which degenerates the nervous system and often leads to incapacitation. Multi-drug therapy which consists of dapsone, rifampicin and clofazimine has been effective to combat this disease. In Indonesia, especially in Papua Island, leprosy is still a problem. Furthermore, there had been higher reports of Dapsone Hypersensitivity Syndrome (DHS) which also challenges...

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Identifiers

PMID: 33064728
DOI: 10.1371/journal.pntd.0008746
PMCID: PMC7592909

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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