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Genetic dissection of<i>HLA-DRB1*15:01</i>and XL9 region variants in Japanese patients with systemic lupus erythematosus: Primary role for<i>HLA-DRB1*15:01</i>

2023-04-05

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> Major histocompatibility complex strongly contributes to susceptibility to systemic lupus erythematosus (SLE). In the European populations, HLA-DRB1*03:01 and DRB1*15:01 are susceptibility alleles, but C4 locus was reported to account for the association of DRB1*03:01 . With respect to DRB1*15:01 , strong linkage disequilibrium (LD) with a variant rs2105898T in the XL9 region,...

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Literature Corpus work
8f620f85-6f3b-5f50-a1f0-9e3e3f49d245
DOI
10.1101/2023.04.05.23288103
Open publication

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Genetic dissection of<i>HLA-DRB1*15:01</i>and XL9 region variants in Japanese patients with systemic lupus erythematosus: Primary role for<i>HLA-DRB1*15:01</i>DOI 10.1101/2023.04.05.23288103
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