Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic dissection of HLA-DRB115:01 and XL9 region variants in Japanese patients with systemic lupus erythematosus: primary role for HLA-DRB115:01.

RMD open - 1 May 2023

Kawasaki Aya, Kusumawati Premita Ari, Kawamura Yuka, Kondo Yuya, Kusaoi Makio, Amano Hirofumi, Kusanagi Yasuyoshi, Itoh Kenji, Fujimoto Takashi, Tamura Naoto, Hashimoto Hiroshi, Matsumoto Isao, Sumida Takayuki, Tsuchiya Naoyuki

Abstract excerpt

OBJECTIVE: Major histocompatibility complex strongly contributes to susceptibility to systemic lupus erythematosus (SLE). In the European populations, HLA-DRB1*03:01 and DRB1*15:01 are susceptibility alleles, but C4 locus was reported to account for the association of DRB1*03:01. With respect to DRB1*15:01, strong linkage disequilibrium with a variant rs2105898T in the XL9 region, located between DRB1 and DQA1...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to East Asian People
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to HLA-DRB1 Chains

Share to Lupus Erythematosus, Systemic

Source

Open in PubMed Open full text

Identifiers

PMID: 37258043
DOI: 10.1136/rmdopen-2023-003214
PMCID: PMC10255040

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic dissection of HLA-DRB1*15:01 and XL9 region variants in Japanese patients with systemic lupus erythematosus: primary role for HLA-DRB1*15:01.PMID 37258043Read ↗

Genetic dissection of<i>HLA-DRB1*15:01</i>and XL9 region variants in Japanese patients with systemic lupus erythematosus: Primary role for<i>HLA-DRB1*15:01</i>Semantic proximity Read ↗

Association of HLA-G 3' Untranslated Region Polymorphisms with Systemic Lupus Erythematosus in a Japanese Population: A Case-Control Association Study.Semantic proximity Read ↗

Association of HLA-DR3 and HLA-DR15 Polymorphisms with Risk of Systemic Lupus ErythematosusSemantic proximity Read ↗

Human leukocyte antigens and systemic lupus erythematosus: a protective role for the HLA-DR6 alleles DRB1*13:02 and *14:03.Semantic proximity Read ↗

An association analysis of HLA-DRB1 with systemic lupus erythematosus and rheumatoid arthritis in a Japanese population: effects of *09:01 allele on disease phenotypes.Semantic proximity Read ↗

Deconstruction of HLA-DRB1*04:01:01 and HLA-DRB1*15:01:01 class II haplotypes using next-generation sequencing in European-Americans with multiple sclerosisSemantic proximity Read ↗

Amino acid signatures of HLA Class-I and II molecules are strongly associated with SLE susceptibility and autoantibody production in Eastern AsiansSemantic proximity Read ↗

Association of HLA-DRB1*15 and HLADQB1*06 with SLE in Saudis.Semantic proximity Read ↗

Association of HLA-DR1, HLA-DR13, and HLA-DR16 Polymorphisms with Systemic Lupus Erythematosus: A Meta-Analysis.Semantic proximity Read ↗

A novel HLA allele derived from a likely DRB1/DRB3 gene conversion event: HLA-DRB3*01:15.Semantic proximity Read ↗

Evidence for an association of HLA-DRB1*15 and DRB1*09 with leprosy and the impact of DRB1*09 on disease onset in a Chinese Han population.Semantic proximity Read ↗

B cell polygenic risk scores associate with anti-dsDNA antibodies and nephritis in systemic lupus erythematosusSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.