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Article

Role of inducible nitric oxide synthase in asthma risk and lung function growth during adolescence.

Thorax - 1 Feb 2010

Islam Talat, Breton Carrie, Salam Muhammad T, McConnell Rob, Wenten Made, Gauderman W James, Conti David, Van Den Berg David, Peters John M, Gilliland Frank D

Abstract excerpt

BACKGROUND: Inducible nitric oxide (NO) synthase (iNOS, encoded by NOS2A) produces NO in response to environmental stimuli, which can result in nitrosative stress. Because nitrosative stress affects respiratory health, it was hypothesised that variants in NOS2A are associated with asthma incidence and lung function growth during adolescence. METHODS: In this prospective study, spirometric testing was performed at...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19996333
DOI: 10.1136/thx.2009.114355

Genes

FEV
GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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