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Article

Genetic polymorphisms in the treatment of depression: speculations from an augmentation study using atomoxetine.

Psychiatry research - 30 Jan 2010

Reimherr Frederick, Amsterdam Jay, Dunner David, Adler Lenard, Zhang Shuyu, Williams David, Marchant Barrie, Michelson David, Nierenberg Andrew, Schatzberg Alan, Feldman Peter

Abstract excerpt

Treatment-resistant depression may be related to polymorphisms in the promoter region of the serotonin transporter gene (5-HTTLPR) or dysregulation of noradrenergic systems. To examine 5-HTTLPR genotypes and responses to treatment, adult patients (N=261) with current major depression and a sympto...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19969374
DOI: 10.1016/j.psychres.2009.01.005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19969374-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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