Article
Serotonin transporter polymorphisms and adverse effects with fluoxetine treatment.
Biological psychiatry - 1 Nov 2003
Perlis Roy H, Mischoulon David, Smoller Jordan W, Wan Yu-Jui Yvonne, Lamon-Fava Stefania, Lin Keh-Ming, Rosenbaum Jerrold F, Fava Maurizio
Abstract excerpt
BACKGROUND: The short (S) allele of the serotonin transporter gene-linked polymorphic region (5HTTLPR) has been associated with poorer antidepressant response in major depressive disorder (MDD) and with antidepressant-induced mania. This study investigated a possible association with treatment-emergent insomnia or agitation. METHODS: Thirty-six outpatients with MDD were genotyped at 5HTTLPR and treated with...
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