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Article

Phosducin influences sympathetic activity and prevents stress-induced hypertension in humans and mice.

The Journal of clinical investigation - 1 Dec 2009

Beetz Nadine, Harrison Michael D, Brede Marc, Zong Xiangang, Urbanski Michal J, Sietmann Anika, Kaufling Jennifer, Lorkowski Stefan, Barrot Michel, Seeliger Mathias W, Vieira-Coelho Maria Augusta, Hamet Pavel, Gaudet Daniel, Seda Ondrej, Tremblay Johanne, Kotchen Theodore A, Kaldunski Mary, Nüsing Rolf, Szabo Bela, Jacob Howard J, Cowley Allen W, Biel Martin, Stoll Monika, Lohse Martin J, Broeckel Ulrich, Hein Lutz

Abstract excerpt

Hypertension and its complications represent leading causes of morbidity and mortality. Although the cause of hypertension is unknown in most patients, genetic factors are recognized as contributing significantly to an individual's lifetime risk of developing the condition. Here, we investigated...

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Identifiers

PMID: 19959875
DOI: 10.1172/JCI38433
PMCID: PMC2786789

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Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19959875-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Phosducin influences sympathetic activity and prevents stress-induced hypertension in humans and mice.PMID 19959875Read ↗

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