Article
The identification of phosducin as a novel candidate gene for hypertension and its role in sympathetic activation.
Current opinion in nephrology and hypertension - 1 Mar 2011
Broeckel Ulrich, Stoll Monika, Hein Lutz
Abstract excerpt
PURPOSE OF REVIEW: The primary objective of this review is to familiarize readers with the recent identification of phosducin (Pdc) as a novel candidate gene for stress-induced hypertension using comparative genetics and the elucidation of its role in sympathetic activation. RECENT FINDINGS: Phosducin was previously identified as a G-protein regulator expressed in the retina and pineal gland. Knowledge of its...
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