Article
Phosducin rs12402521 polymorphism predicts development of hypertension in young subjects with overweight or obesity.
Nutrition, metabolism, and cardiovascular diseases : NMCD - 1 Apr 2013
Palatini P, Ceolotto G, Ragazzo F, Mos L, Santonastaso M, Zanata G, Saladini F, Casiglia E
Abstract excerpt
BACKGROUND AND AIMS: The G-protein regulator phosducin has been shown to be associated with stress-dependent blood pressure, but whether obesity is a modulator of the relationship between phosducin and risk of hypertension is unknown. We studied the effect of two phosducin polymorphisms on risk of hypertension in 273 overweight or obese (Ov-Ob) young-to-middle-age participants from the HARVEST and 287 normal...
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