Article

Novel target identification using single cell sequencing and electrophysiology of cardiac sympathetic neurons in disease

2019-12-11

Abstract excerpt

The activity of cardiac sympathetic nerves from the stellate ganglia is increased in many cardiovascular diseases contributing to the pathophysiology, however the mechanisms underlying this are unknown. Moreover, clinical studies show their surgical removal is an effective treatment, despite the biophysical properties of these neurons being largely unstudied. Here we demonstrate that stellate ganglia neurons from...

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Literature Corpus work: 3fc70ab5-fe5d-58d7-81f0-4c02aa688f5a
DOI: 10.1101/2019.12.11.872580

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