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Article

Morphogenetic and regulatory effects of mutations in the envelope proteins of an avian hepadnavirus.

Journal of virology - 1 Mar 1991

Summers J, Smith P M, Huang M J, Yu M S

Abstract excerpt

The envelope gene of the avian hepadnavirus, duck hepatitis B virus, was mutated in order to dissect the functions of the two major envelope proteins pre-S/S and S. Both envelope proteins were found to be required for virus particle assembly and secretion. The placement of stop codons after each of the first three AUG codons in the pre-S region allowed efficient translational initiation at downstream AUG codons...

Topics

Animals
Cell Line
Chickens
DNA Replication
DNA, Viral
Hepatitis B Virus, Duck
Morphogenesis
Mutagenesis, Site-Directed
Phenotype
Restriction Mapping
Transfection
Viral Envelope Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 1995945
DOI: 10.1128/JVI.65.3.1310-1317.1991
PMCID: PMC239906

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1995945-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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