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Article

Coat Protein Mutations That Alter the Flux of Morphogenetic Intermediates through the ϕX174 Early Assembly Pathway.

Journal of virology - 15 Dec 2017

Blackburn Brody J, Li Shuaizhi, Roznowski Aaron P, Perez Alexis R, Villarreal Rodrigo H, Johnson Curtis J, Hardy Margaret, Tuckerman Edward C, Burch April D, Fane Bentley A

Abstract excerpt

Two scaffolding proteins orchestrate ϕX174 morphogenesis. The internal scaffolding protein B mediates the formation of pentameric assembly intermediates, whereas the external scaffolding protein D organizes 12 of these intermediates into procapsids. Aromatic amino acid side chains mediate most coat-internal scaffolding protein interactions. One residue in the internal scaffolding protein and three in the coat...

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Source

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Identifiers

PMID: 28978706
DOI: 10.1128/JVI.01384-17
PMCID: PMC5709602

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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