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Article

The virological and clinical significance of mutations in the overlapping envelope and polymerase genes of hepatitis B virus.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Aug 2002

Torresi Joseph

Abstract excerpt

The potential for hepatitis B virus (HBV) to alter its genome is considerable. This occurs because the virus utilizes a reverse transcription step in replicating the viral genome. Like human immunodeficiency virus, the reverse transcriptase of HBV is error prone and as a consequence of specific selection pressures within a host a population of viral quasispecies emerges. HBV mutants with survival advantages over...

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Identifiers

PMID: 12367644
DOI: 10.1016/s1386-6532(02)00049-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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