Sequence- and structure-specific determinants in the interaction between the RNA encapsidation signal and reverse transcriptase of avian hepatitis B viruses.

Abstract excerpt

Hepatitis B viruses (HBVs) replicate by reverse transcription of an RNA intermediate. Packaging of this RNA pregenome into nucleocapsids and replication initiation depend crucially on the interaction of the reverse transcriptase, P protein, with the cis-acting, 5' end-proximal encapsidation signa...

Topics

• Animals
• Avihepadnavirus
• Base Sequence
• Binding Sites
• Conserved Sequence
• Gene Products, pol
• Hepatitis B Virus, Duck
• Molecular Sequence Data
• Mutation
• Nucleic Acid Conformation
• RNA, Viral
• Structure-Activity Relationship
• Virus Assembly