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Article

Increased trisomy 12 frequency and a biased IgVH 3-21 gene usage characterize small lymphocytic lymphoma.

Leukemia research - 1 May 2010

Daudignon Agnès, Poulain Stéphanie, Morel Pierre, Penther Dominique, Parmentier Françoise, Bouchindhomme Brigitte, Fernandes José, Duthilleul Patrick, Bastard Christian

Abstract excerpt

Small lymphocytic lymphoma (SLL) and chronic lymphocytic leukemia (CLL) are considered as similar entity by the WHO classification. We assessed the distribution of the four prognostic cytogenetic markers (deletion 11q23, 13q14, 17p13 and trisomy 12) and VH mutational status in 32 SLL and 119 CLL....

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Share to Chromosomes, Human, Pair 12
Share to Genes, Immunoglobulin Heavy Chain

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunoglobulin Variable Region

Share to In Situ Hybridization, Fluorescence

Share to Kaplan-Meier Estimate

Share to Leukemia, Lymphocytic, Chronic, B-Cell

Share to Neoplasm Staging

Share to Trisomy

Source

Identifiers

PMID: 19959229
DOI: 10.1016/j.leukres.2009.11.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19959229-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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