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Article

Combined patterns of IGHV repertoire and cytogenetic/molecular alterations in monoclonal B lymphocytosis versus chronic lymphocytic leukemia.

PloS one - 1 Jan 2013

Henriques Ana, Rodríguez-Caballero Arancha, Nieto Wendy G, Langerak Anton W, Criado Ignacio, Lécrevisse Quentin, González Marcos, Pais Maria L, Paiva Artur, Almeida Julia, Orfao Alberto

Abstract excerpt

BACKGROUND: Chronic lymphocytic leukemia (CLL)-like monoclonal B lymphocytosis (MBL) with (MBL(hi)) or without (MBL(lo)) absolute B-lymphocytosis precedes most CLL cases,the specific determinants for malignant progression remaining unknown. METHODOLOGY/PRINCIPAL FINDINGS: For this purpose, simultaneous iFISH and molecular analysis of well-established cytogenetic alterations of chromosomes 11, 12, 13, 14 and 17...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Leukemia, Lymphocytic, Chronic, B-Cell

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Source

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Identifiers

PMID: 23844084
DOI: 10.1371/journal.pone.0067751
PMCID: PMC3701012

Genes

BCR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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