Article
Characterization of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) in Shanghai, China: molecular and cytogenetic characteristics, IgV gene restriction and hypermutation patterns.
Leukemia research - 1 Dec 2009
Irons Richard D, Le Anh, Bao Liming, Zhu Xiongzeng, Ryder John, Wang Xiao Qin, Ji Meirong, Chen Yan, Wu Xichun, Lin Guowei
Abstract excerpt
The clinical, cytogenetic and molecular features of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), a disease previously considered to be rare in Asia, were examined in consecutive series of 70 cases diagnosed by our laboratory over a 30-month period. Clonal abnormalities were observed in 80% of CLL/SLL cases using a combination of conventional cytogenetic and fluorescence in situ hybridization...
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