Article
Oxidative stress studies in yeast with a frataxin mutant: a proteomics perspective.
Journal of proteome research - 5 Feb 2010
Kim Jin-Hee, Sedlak Miroslav, Gao Qiang, Riley Catherine P, Regnier Fred E, Adamec Jiri
Abstract excerpt
Cellular response of wild-type Saccharomyces cerevisiae and the Delta yfh1 mutant to oxidative stress (OS) was examined by stressing cells through the addition of H(2)O(2) to the growth medium. The Delta yfh1 mutant is unusual in that it accumulates iron in it is mitochondria. Wild-type growth was immediately arrested and recovered in 2 h following H(2)O(2) treatment. No change in viability was observed. Growth...
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