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Article

Evidence that yeast frataxin is not an iron storage protein in vivo.

Biochimica et biophysica acta - 1 Jun 2010

Seguin Alexandra, Sutak Robert, Bulteau Anne-Laure, Garcia-Serres Richard, Oddou Jean-Louis, Lefevre Sophie, Santos Renata, Dancis Andrew, Camadro Jean-Michel, Latour Jean-Marc, Lesuisse Emmanuel

Abstract excerpt

Yeast cells deficient in the yeast frataxin homolog (Yfh1p) accumulate iron in their mitochondria. Whether this iron is toxic, however, remains unclear. We showed that large excesses of iron in the growth medium did not inhibit growth and did not decrease cell viability. Increasing the ratio of m...

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Identifiers

PMID: 20307653
DOI: 10.1016/j.bbadis.2010.03.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20307653-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Evidence that yeast frataxin is not an iron storage protein in vivo.PMID 20307653Read ↗

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