Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of 5p15.33 (TERT-CLPTM1L), 6p21.33 and 15q25.1 (CHRNA5-CHRNA3) variation and lung cancer risk in never-smokers.

Carcinogenesis - 1 Feb 2010

Wang Yufei, Broderick Peter, Matakidou Athena, Eisen Timothy, Houlston Richard S

Abstract excerpt

Genome-wide association studies have provided evidence that common variation at 5p15.33 (TERT-CLPTM1L), 6p21.33 and 15q25.1 (CHRNA5-CHRNA3) influences lung cancer risk. To examine if variation at any of these loci influences the risk of lung cancer in never-smokers, we compared 5p15.33-TERT (rs27...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Squamous Cell
Share to Chromosomes, Human, Pair 15

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 5

Share to Chromosomes, Human, Pair 6

Share to Molecular Chaperones

Share to Receptors, Nicotinic

Share to Survival Rate

Share to Telomerase

Source

Identifiers

PMID: 19955392
DOI: 10.1093/carcin/bgp287

Genes

CHRNA3
TERT
CHRNA5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19955392-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of 5p15.33 (TERT-CLPTM1L), 6p21.33 and 15q25.1 (CHRNA5-CHRNA3) variation and lung cancer risk in never-smokers.PMID 19955392Read ↗

The 5p15.33 locus is associated with risk of lung adenocarcinoma in never-smoking females in Asia.Semantic proximity Read ↗

Lung cancer susceptibility locus at 5p15.33.Semantic proximity Read ↗

Common 5p15.33 and 6p21.33 variants influence lung cancer risk.Semantic proximity Read ↗

Common genetic variants on 5p15.33 contribute to risk of lung adenocarcinoma in a Chinese population.Semantic proximity Read ↗

Novel genetic variants in the chromosome 5p15.33 region associate with lung cancer risk.Semantic proximity Read ↗

TERT-rs33963617 and CLPTM1L-rs77518573 reduce the risk of non-small cell lung cancer in Chinese population.Semantic proximity Read ↗

Multiple variants of TERT and CLPTM1L constitute risk factors for lung adenocarcinoma.Semantic proximity Read ↗

The TERT-CLPTM1L locus for lung cancer predisposes to bronchial obstruction and emphysema.Semantic proximity Read ↗

Significant association of 5p15.33 (TERT-CLPTM1L genes) with lung cancer in Chinese Han population.Semantic proximity Read ↗

Study of genetic variants in chromosome 5p15.33 region in non-smoker lung cancer patients.Semantic proximity Read ↗

A genetic sequence variant (GSV) at susceptibility loci of 5p15.33 (TERT-CLPTM1L) is associated with survival outcome in locally advanced and metastatic non-small-cell lung cancer (NSCLC).Semantic proximity Read ↗

Fine-mapping of the 5p15.33, 6p22.1-p21.31, and 15q25.1 regions identifies functional and histology-specific lung cancer susceptibility loci in African-Americans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.