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Article

The TERT-CLPTM1L locus for lung cancer predisposes to bronchial obstruction and emphysema.

The European respiratory journal - 1 Oct 2011

Wauters E, Smeets D, Coolen J, Verschakelen J, De Leyn P, Decramer M, Vansteenkiste J, Janssens W, Lambrechts D

Abstract excerpt

Clinical studies suggest that bronchial obstruction and emphysema increase susceptibility to lung cancer. We assessed the possibility of a common genetic origin and investigated whether the lung cancer susceptibility locus on chromosome 5p15.33 increases the risk for bronchial obstruction and emphysema. Three variants in the 5p15.33 locus encompassing the TERT and CLPTM1L genes were genotyped in 777 heavy smokers...

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Source

Identifiers

PMID: 21622582
DOI: 10.1183/09031936.00187110

Genes

TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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The TERT-CLPTM1L locus for lung cancer predisposes to bronchial obstruction and emphysema.PMID 21622582Read ↗

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Multiple variants of TERT and CLPTM1L constitute risk factors for lung adenocarcinoma.Semantic proximity Read ↗

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Novel genetic variants in the chromosome 5p15.33 region associate with lung cancer risk.Semantic proximity Read ↗

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