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Multiple variants of TERT and CLPTM1L constitute risk factors for lung adenocarcinoma.

Genetics and molecular research : GMR - 16 Feb 2012

Chen X F, Cai S, Chen Q G, Ni Z H, Tang J H, Xu D W, Wang X B

Abstract excerpt

Recent studies have shown that 5p15.33 is one of the chromosomal regions that is most consistently altered in lung cancer; common variants that are located in this region have been genotyped in various populations. However, the genetic contribution of these variants to carcinogenesis is relatively unknown. A clinic-based case-control study in Shanghai was undertaken on 196 patients with lung cancer and 229...

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Identifiers

PMID: 22370939
DOI: 10.4238/2012.February.16.2

Genes

TERT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Multiple variants of TERT and CLPTM1L constitute risk factors for lung adenocarcinoma.PMID 22370939Read ↗

Common genetic variants on 5p15.33 contribute to risk of lung adenocarcinoma in a Chinese population.Semantic proximity Read ↗

Lung cancer susceptibility locus at 5p15.33.Semantic proximity Read ↗

The 5p15.33 locus is associated with risk of lung adenocarcinoma in never-smoking females in Asia.Semantic proximity Read ↗

Genetic variant rs401681 at 5p15.33 modifies susceptibility to lung cancer but not esophageal squamous cell carcinoma.Semantic proximity Read ↗

Association between TERT rs2736100 polymorphism and lung cancer susceptibility: evidence from 22 case-control studies.Semantic proximity Read ↗

Genetic variations in TERT-CLPTM1L locus are associated with risk of lung cancer in Chinese population.Semantic proximity Read ↗

Association of genetic polymorphisms in TERT-CLPTM1L with lung cancer in a Chinese population.Semantic proximity Read ↗

TERT-rs33963617 and CLPTM1L-rs77518573 reduce the risk of non-small cell lung cancer in Chinese population.Semantic proximity Read ↗

Significant association of 5p15.33 (TERT-CLPTM1L genes) with lung cancer in Chinese Han population.Semantic proximity Read ↗

Role of 5p15.33 (TERT-CLPTM1L), 6p21.33 and 15q25.1 (CHRNA5-CHRNA3) variation and lung cancer risk in never-smokers.Semantic proximity Read ↗

A genetic sequence variant (GSV) at susceptibility loci of 5p15.33 (TERT-CLPTM1L) is associated with survival outcome in locally advanced and metastatic non-small-cell lung cancer (NSCLC).Semantic proximity Read ↗

Novel genetic variants in the chromosome 5p15.33 region associate with lung cancer risk.Semantic proximity Read ↗

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