Article
Essential roles of three enhancer sites in sigma54-dependent transcription by the nitric oxide sensing regulatory protein NorR.
Nucleic acids research - 1 Mar 2010
Tucker Nicholas P, Ghosh Tamaswati, Bush Matthew, Zhang Xiaodong, Dixon Ray
Abstract excerpt
The bacterial activator protein NorR binds to enhancer-like elements, upstream of the promoter site, and activates sigma(54)-dependent transcription of genes that encode nitric oxide detoxifying enzymes (NorVW), in response to NO stress. Unique to the norVW promoter in Escherichia coli is the presence of three enhancer sites associated with a binding site for sigma(54)-RNA polymerase. Here we show that all three...
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