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Article

DSIF, the Paf1 complex, and Tat-SF1 have nonredundant, cooperative roles in RNA polymerase II elongation.

Genes & development - 1 Dec 2009

Chen Yexi, Yamaguchi Yuki, Tsugeno Yuta, Yamamoto Junichi, Yamada Tomoko, Nakamura Mitsuhiro, Hisatake Koji, Handa Hiroshi

Abstract excerpt

Transcription elongation factor DSIF/Spt4-Spt5 is capable of promoting and inhibiting RNA polymerase II elongation and is involved in the expression of various genes. While it has been known for many years that DSIF inhibits elongation in collaboration with the negative elongation factor NELF, ho...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 19952111
DOI: 10.1101/gad.1834709
PMCID: PMC2788331

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19952111-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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DSIF, the Paf1 complex, and Tat-SF1 have nonredundant, cooperative roles in RNA polymerase II elongation.PMID 19952111Read ↗

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