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Article

Identification and characterization of Elf1, a conserved transcription elongation factor in Saccharomyces cerevisiae.

Molecular and cellular biology - 1 Nov 2005

Prather Donald, Krogan Nevan J, Emili Andrew, Greenblatt Jack F, Winston Fred

Abstract excerpt

In order to identify previously unknown transcription elongation factors, a genetic screen was carried out to identify mutations that cause lethality when combined with mutations in the genes encoding the elongation factors TFIIS and Spt6. This screen identified a mutation in YKL160W, hereafter named ELF1 (elongation factor 1). Further analysis identified synthetic lethality between an elf1Delta mutation and...

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Source

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Identifiers

PMID: 16260625
DOI: 10.1128/MCB.25.22.10122-10135.2005
PMCID: PMC1280281

Genes

ELF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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