Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Proteomics of the eukaryotic transcription machinery: identification of proteins associated with components of yeast TFIID by multidimensional mass spectrometry.

Molecular and cellular biology - 1 Jul 2002

Sanders Steven L, Jennings Jennifer, Canutescu Adrian, Link Andrew J, Weil P Anthony

Abstract excerpt

The general transcription factor TFIID is a multisubunit complex of TATA-binding protein (TBP) and 14 distinct TBP-associated factors (TAFs). Although TFIID constituents are required for transcription initiation of most mRNA encoding genes, the mechanism of TFIID action remains unclear. To gain insight into TFIID function, we sought to generate a proteomic catalogue of proteins specifically interacting with TFIID...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromatography, Liquid
Share to Immunochemistry

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Proteome

Share to TATA-Binding Protein Associated Factors

Share to TATA-Box Binding Protein

Share to Transcription Factor TFIID

Share to Transcription Factors, TFII

Share to Yeasts

Source

Open in PubMed Open full text

Identifiers

PMID: 12052880
DOI: 10.1128/MCB.22.13.4723-4738.2002
PMCID: PMC133885

Genes

TBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Proteomics of the eukaryotic transcription machinery: identification of proteins associated with components of yeast TFIID by multidimensional mass spectrometry.PMID 12052880Read ↗

Architecture of TAF11/TAF13/TBP complex suggests novel regulatory state in General Transcription Factor TFIID functionSemantic proximity Read ↗

Identifying a TFIID interactome via integrated biochemical and high-throughput proteomic studiesSemantic proximity Read ↗

Distinct mutations in yeast TAF(II)25 differentially affect the composition of TFIID and SAGA complexes as well as global gene expression patterns.Semantic proximity Read ↗

Genome-wide localization analysis of a complete set of Tafs reveals a specific effect of the taf1 mutation on Taf2 occupancy and provides indirect evidence for different TFIID conformations at different promoters.Semantic proximity Read ↗

The TAF9 C-terminal conserved region domain is required for SAGA and TFIID promoter occupancy to promote transcriptional activation.Semantic proximity Read ↗

TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.Semantic proximity Read ↗

Identification of a yeast transcription factor IID subunit, TSG2/TAF48.Semantic proximity Read ↗

Broad, but not universal, transcriptional requirement for yTAFII17, a histone H3-like TAFII present in TFIID and SAGA.Semantic proximity Read ↗

Functional specialization of two paralogous TAF12 variants by their selective association with SAGA and TFIID transcriptional regulatory complexesSemantic proximity Read ↗

TFIIA interacts with TFIID via association with TATA-binding protein and TAF40.Semantic proximity Read ↗

Proteomics studies of the interactome of RNA polymerase II C-terminal repeated domain.Semantic proximity Read ↗

Molecular genetic dissection of TAF25, an essential yeast gene encoding a subunit shared by TFIID and SAGA multiprotein transcription factors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.