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Article

Confirmation of the genetic association of CTLA4 and PTPN22 with ANCA-associated vasculitis.

BMC medical genetics - 1 Dec 2009

Carr Edward J, Niederer Heather A, Williams Julie, Harper Lorraine, Watts Richard A, Lyons Paul A, Smith Kenneth G C

Abstract excerpt

BACKGROUND: The genetic contribution to the aetiology of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is not well defined. Across different autoimmune diseases some genes with immunomodulatory roles, such as PTPN22, are frequently associated with multiple diseases, whereas specific HLA associations, such as HLA-B27, tend to be disease restricted. We studied ten candidate loci on the...

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Share to Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Share to Antibodies, Antineutrophil Cytoplasmic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antigens, CD

Share to Cohort Studies

Share to CTLA-4 Antigen

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Share to Protein Tyrosine Phosphatase, Non-Receptor Type 22

Source

Open in PubMed Open full text

Identifiers

PMID: 19951419
DOI: 10.1186/1471-2350-10-121
PMCID: PMC3224698

Genes

PTPN22
CTLA4
ERBB3
IFIH1
PTPN2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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