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Article

PTPN22 and CTLA-4 Polymorphisms Are Associated With Polyglandular Autoimmunity.

The Journal of clinical endocrinology and metabolism - 1 May 2018

Houcken Juliane, Degenhart Christina, Bender Klaus, König Jochem, Frommer Lara, Kahaly George J

Abstract excerpt

Context: Single nucleotide polymorphisms (SNPs) of various genes increase susceptibility to monoglandular autoimmunity. Data on autoimmune polyglandular syndromes (APSs) are scarce. Objective: Evaluate potential associations of eight SNPs with APSs. Setting: Academic referral endocrine clinic. Patients: A total of 543 patients with APS and monoglandular autoimmunity and controls. Intervention: The SNP protein...

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Topics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polyendocrinopathies, Autoimmune

Share to Polymorphism, Single Nucleotide

Share to Protein Tyrosine Phosphatase, Non-Receptor Type 22

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Source

Identifiers

PMID: 29409002
DOI: 10.1210/jc.2017-02577

Genes

PTPN22
VDR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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