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Article

Association of a single nucleotide polymorphism in the C-reactive protein gene (-286) with susceptibility to Plasmodium falciparum malaria.

Molecular medicine (Cambridge, Mass.) - 1 Jan 2000

Giha Hayder A, Nasr Amre, Ekström Mattias, Israelsson Elisabeth, Arambepola Gishanthi, Arnot David, Theander Thor G, Troye-Blomberg Marita, Berzins Klavs, Tornvall Per, ElGhazali Gehad

Abstract excerpt

The role of inflammation in malaria pathogenesis is not fully understood, although C-reactive protein (CRP) may have a negative influence on host immunity to infections. An upstream polymorphism, -286 (C > T > A), in the CRP gene is known to influence CRP levels. In this study, a cohort of 192 Su...

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Identifiers

PMID: 19946607
DOI: 10.2119/molmed.2009.00136
PMCID: PMC2781302

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CRP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19946607-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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