Article
Genome-wide scan of the effect of common nsSNPs on colorectal cancer survival outcome.
British journal of cancer - 1 Oct 2018
Theodoratou Evropi, Farrington Susan M, Timofeeva Maria, Din Farhat Vn, Svinti Victoria, Tenesa Albert, Liu Tao, Lindblom Annika, Gallinger Steven, Campbell Harry, Dunlop Malcolm G
Abstract excerpt
BACKGROUND: We conducted a genome-wide scan to identify non-synonymous SNPs (nsSNPs) that might influence survival after a diagnosis of colorectal cancer (CRC). METHODS: We genotyped 7679 nsSNPs in 1939 Scottish patients from the Scottish Colorectal Cancer Study recruited soon after a CRC diagnosis and prospectively followed for survival outcomes. All-cause and CRC-specific survival analyses were conducted using...
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