Article
Vitamin D receptor polymorphism and colorectal cancer-specific and all-cause mortality.
Cancer epidemiology - 1 Dec 2013
Perna Laura, Hoffmeister Michael, Schöttker Ben, Arndt Volker, Haug Ulrike, Holleczek Bernd, Burwinkel Barbara, Ordóñez-Mena José M, Brenner Hermann
Abstract excerpt
BACKGROUND: The vitamin D receptor (VDR) gene is present in colorectal cancer (CRC) cells and its genetic variants have been associated with an increased risk of CRC. The association with colorectal cancer prognosis remains widely unexplored. METHODS: 1397 colorectal cancer patients participating in two cancer cohorts (ESTHER II and VERDI) and in a population-based case-control study (DACHS) were followed for 5...
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