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Article

Synergistic effect of TGF‐β superfamily members on the induction of Foxp3<sup>+</sup> Treg

27 Nov 2009

Abstract excerpt

TGF-beta plays an important role in the induction of Treg and maintenance of immunologic tolerance, but whether other members of TGF-beta superfamily act together or independently to achieve this effect is poorly understood. Although others have reported that the bone morphogenetic proteins (BMP) and TGF-beta have similar effects on the development of thymocytes and T cells, in this study, we report that members...

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PMID: 19943263
DOI: 10.1002/eji.200939618

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