Article
Beneficial effects of growth hormone-releasing peptide on myocardial oxidative stress and left ventricular dysfunction in dilated cardiomyopathic hamsters.
Circulation journal : official journal of the Japanese Circulation Society - 1 Jan 2010
Kato Yosuke, Iwase Mitsunori, Ichihara Sahoko, Kanazawa Hiroaki, Hashimoto Katsunori, Noda Akiko, Nagata Kohzo, Koike Yasuo, Yokota Mitsuhiro
Abstract excerpt
BACKGROUND: Growth hormone-releasing peptide (GHRP) may act directly on the myocardium and improve left ventricular (LV) function, suggesting a potential new approach to the treatment of cardiomyopathic hearts. The present study tested the hypothesis that the beneficial cardiac effects of GHRP might include attenuation of myocardial oxidative stress. METHODS AND RESULTS: Dilated cardiomyopathic TO-2 hamsters were...
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