Article
Differential myolysis of myocardium and skeletal muscle in hamsters with dilated cardiomyopathy: beneficial protective effect of diltiazem.
Circulation journal : official journal of the Japanese Circulation Society - 1 Nov 2006
Kato Yosuke, Iwase Mitsunori, Takagi Kenji, Nishizawa Takao, Kanazawa Hiroaki, Matsushita Aya, Umeda Hisashi, Izawa Hideo, Noda Akiko, Koike Yasuo, Nagata Kohzo, Yokota Mitsuhiro
Abstract excerpt
BACKGROUND: Although dilated cardiomyopathic hamsters (TO-2) with mutation of the delta-sarcoglycan gene exhibit histological features of muscular dystrophy, it remains to be elucidated whether both myocardium and skeletal muscle are injured in a similar manner. METHODS AND RESULTS: The progression of myolysis in both myocardium and skeletal muscle were assessed biochemically and pathologically in TO-2 and F1B...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
