The genetics of major depression: moving beyond the monoamine hypothesis.

Abstract excerpt

Efforts to unlock the biology of major depressive disorder (MDD) are proceeding on multiple fronts. In this article, the authors review the current understanding of epidemiological evidence for a heritable component to MDD risk, as well as recent advances in linkage, candidate gene, and genome-wide association analyses of MDD and related disease subtypes and endophenotypes. While monoamine signaling has...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Depressive Disorder, Major
• Share to Gene Expression
• Share to Genetic Linkage