Genome-wide association study of major recurrent depression in the U.K. population.

doi:10.1176/appi.ajp.2010.09091380

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Article

Genome-wide association study of major recurrent depression in the U.K. population.

The American journal of psychiatry - 1 Aug 2010

Lewis Cathryn M, Ng Mandy Y, Butler Amy W, Cohen-Woods Sarah, Uher Rudolf, Pirlo Katrina, Weale Michael E, Schosser Alexandra, Paredes Ursula M, Rivera Margarita, Craddock Nicholas, Owen Mike J, Jones Lisa, Jones Ian, Korszun Ania, Aitchison Katherine J, Shi Jianxin, Quinn John P, Mackenzie Alasdair, Vollenweider Peter, Waeber Gerard, Heath Simon, Lathrop Mark, Muglia Pierandrea, Barnes Michael R, Whittaker John C, Tozzi Federica, Holsboer Florian, Preisig Martin, Farmer Anne E, Breen Gerome, Craig Ian W, McGuffin Peter

Abstract excerpt

OBJECTIVE: Studies of major depression in twins and families have shown moderate to high heritability, but extensive molecular studies have failed to identify susceptibility genes convincingly. To detect genetic variants contributing to major depression, the authors performed a genome-wide association study using 1,636 cases of depression ascertained in the U.K. and 1,594 comparison subjects screened negative for...

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PMID: 20516156
DOI: 10.1176/appi.ajp.2010.09091380

Genes

BICC1
NLGN1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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