Article
Population genetic analysis of large sequence polymorphisms in Plasmodium falciparum blood-stage antigens.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Mar 2010
Ahouidi Ambroise D, Bei Amy K, Neafsey Daniel E, Sarr Ousmane, Volkman Sarah, Milner Dan, Cox-Singh Janet, Ferreira Marcelo U, Ndir Omar, Premji Zul, Mboup Souleymane, Duraisingh Manoj T
Abstract excerpt
Plasmodium falciparum, the causative agent of human malaria, invades host erythrocytes using several proteins on the surface of the invasive merozoite, which have been proposed as potential vaccine candidates. Members of the multi-gene PfRh family are surface antigens that have been shown to play a central role in directing merozoites to alternative erythrocyte receptors for invasion. Recently, we identified a...
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