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Article

Ace gene dosage influences the development of renovascular hypertension.

Clinical and experimental pharmacology & physiology - 1 Apr 2010

Ceroni Alexandre, Moreira Edson D, Mostarda Cristiano T, Silva Gustavo J J, Krieger Eduardo M, Irigoyen Maria C

Abstract excerpt

1. Clinical and experimental evidence highlights the importance of the renin-angiotensin system in renovascular hypertension. Furthermore, genetic factors affecting angiotensin-converting enzyme (ACE) could influence the development of renovascular hypertension. 2. To test the effect of small gene perturbations on the development of renovascular hypertension, mice harbouring two or three copies of the Ace gene...

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Source

Identifiers

PMID: 19930431
DOI: 10.1111/j.1440-1681.2009.05330.x

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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