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Hepatocarcinoma cells stimulate the growth, migration and expression of pro-angiogenic genes in human hepatic stellate cells

19 Nov 2009

Abstract excerpt

BACKGROUND: Activated hepatic stellate cells (HSC) and other fibrogenic cell types are frequently found around hepatocellular carcinoma. It is unknown whether hepatocarcinoma cells regulate the biological functions of HSC. AIMS: This study aimed to investigate the paracrine effects of hepatocarcinoma cells on human HSC using a co-culture system. METHODS: Huh7 or HepG2 cells, human hepatocarcinoma cell lines, were...

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Share to Hepatocellular Carcinoma Treatment and Prognosis
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PMID: 19929904
DOI: 10.1111/j.1478-3231.2009.02161.x

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