Article
Differential roles of signaling pathways for proliferation and migration of rat pancreatic stellate cells.
The Tohoku journal of experimental medicine - 1 Feb 2003
Masamune Atsushi, Kikuta Kazuhiro, Satoh Masahiro, Kume Kiyoshi, Shimosegawa Tooru
Abstract excerpt
Activated pancreatic stellate cells (PSCs) have recently been implicated in the pathogenesis of pancreatic fibrosis and inflammation. Accumulation of PSCs is a fundamental feature of pancreatic fibrosis, and platelet-derived growth factor (PDGF)-BB is the most potent mitogen for PSCs. But, the mo...
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