Article
Clinical significance and gene expression study of human hepatic stellate cells in HBV related-hepatocellular carcinoma.
Journal of experimental & clinical cancer research : CR - 19 Apr 2013
Liao Rui, Wu Han, Yi Yong, Wang Jia-Xing, Cai Xiao-Yan, He Hong-Wei, Cheng Yun-Feng, Zhou Jian, Fan Jia, Sun Jian, Qiu Shuang-Jian
Abstract excerpt
BACKGROUND: Peritumoral activated hepatic stellate cells (HSCs) are versatile myofibroblast-like cells closely related with hepatocellular carcinoma (HCC) progression. So far, comprehensive comparison of gene expression of human HSCs during hepatocarcinogenesis is scanty. Therefore, we identified the phenotypic and genomic characteristics of peritumoral HSCs to explore the valuable information on the prognosis...
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