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Article

Role of APC and its binding partners in regulating microtubules in mitosis.

Advances in experimental medicine and biology - 1 Jan 2009

Bahmanyar Shirin, Nelson W James, Barth Angela I M

Abstract excerpt

Adenomatous polyposis coli (APC) is a multifunctional protein commonly mutated in colon cancer. APC contains binding sites for multiple proteins with diverse roles in signaling and the structural and functional organization of cells. Recent evidence suggests roles for APC and some of its binding partners in regulating microtubules in mitosis. APC localizes to three key locations in mitosis: kinetochores, the...

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Source

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Identifiers

PMID: 19928353
DOI: 10.1007/978-1-4419-1145-2_6
PMCID: PMC3373726

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

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Role of APC and its binding partners in regulating microtubules in mitosis.PMID 19928353Read ↗

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APC functions at the centrosome to stimulate microtubule growth.Semantic proximity Read ↗

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PLK1 has tumor-suppressive potential in APC-truncated colon cancer cellsSemantic proximity Read ↗

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