Genotype at the sIL-6R A358C polymorphism does not influence response to anti-TNF therapy in patients with rheumatoid arthritis.

doi:10.1093/rheumatology/kep372

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Article

Genotype at the sIL-6R A358C polymorphism does not influence response to anti-TNF therapy in patients with rheumatoid arthritis.

Rheumatology (Oxford, England) - 1 Jan 2010

Hassan Batool, Maxwell James R, Hyrich Kimme L, Barton Anne, Worthington Jane, Isaacs John D, Morgan Ann W, Wilson Anthony G

Abstract excerpt

OBJECTIVES: To investigate the association between genotype at the soluble interleukin 6 receptor (sIL-6R) A358C single nucleotide polymorphism (SNP, rs8192284), previously reported to correlate with soluble receptor levels, and response to anti-TNF therapy in subjects with RA. METHODS: In a larg...

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PMID: 19926672
DOI: 10.1093/rheumatology/kep372

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19926672-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

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