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Article

Lack of replication of genetic predictors for the rheumatoid arthritis response to anti-TNF treatments: a prospective case-only study.

Arthritis research & therapy - 1 Jan 2010

Suarez-Gestal Marian, Perez-Pampin Eva, Calaza Manuel, Gomez-Reino Juan J, Gonzalez Antonio

Abstract excerpt

INTRODUCTION: We aimed to replicate the strong associations that a recent genome wide association study (GWAS) has found between 16 single nucleotide polymorphisms (SNPs) and response to anti-tumour necrosis factor (TNF) treatment in 89 patients with rheumatoid arthritis (RA). This study is very important because, according to published simulations, associations as strong as the reported ones will mean that these...

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Identifiers

PMID: 20423481
DOI: 10.1186/ar2990
PMCID: PMC2888228

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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