Article
Fcgamma receptor type IIIA genotype and response to tumor necrosis factor alpha-blocking agents in patients with rheumatoid arthritis.
Arthritis and rheumatism - 1 Feb 2007
Kastbom Alf, Bratt Johan, Ernestam Sofia, Lampa Jon, Padyukov Leonid, Söderkvist Peter, Skogh Thomas
Abstract excerpt
OBJECTIVE: To determine whether a functional single-nucleotide polymorphism in the gene encoding Fcgamma receptor type IIIA (FcgammaRIIIA) correlates with the response to treatment with tumor necrosis factor alpha inhibitors in rheumatoid arthritis (RA). METHODS: The study population comprised 282 Swedish patients with RA in whom the therapeutic efficacy of conventional disease-modifying antirheumatic drugs had...
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