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Article

Cluster headache is associated with the alcohol dehydrogenase 4 (ADH4) gene.

Headache - 1 Jan 2010

Rainero Innocenzo, Rubino Elisa, Gallone Salvatore, Fenoglio Pierpaola, Negro Elisa, De Martino Paola, Savi Lidia, Pinessi Lorenzo

Abstract excerpt

BACKGROUND/OBJECTIVES: Alcohol is a well-known trigger factor for cluster headache attacks during the active phases of the disease. The alcohol dehydrogenase (ADH) pathway, which converts alcohol to the toxic substance acetaldehyde, is responsible for most of the alcohol breakdown in the liver. H...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19925625
DOI: 10.1111/j.1526-4610.2009.01569.x

Genes

ADH4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19925625-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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