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Article

Genetic association of HCRTR2, ADH4 and CLOCK genes with cluster headache: a Chinese population-based case-control study.

The journal of headache and pain - 9 Jan 2018

Fan Zhiliang, Hou Lei, Wan Dongjun, Ao Ran, Zhao Dengfa, Yu Shengyuan

Abstract excerpt

BACKGROUND: Cluster headache (CH), a rare primary headache disorder, is currently thought to be a genetic susceptibility which play a role in CH susceptibility. A large numbers of genetic association studies have confirmed that the HCRTR2 (Hypocretin Receptor 2) SNP rs2653349, and the ADH4 (Alcohol Dehydrogenase 4) SNP rs1126671 and rs1800759 polymorphisms are linked to CH. In addition, the CLOCK (Circadian...

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Source

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Identifiers

PMID: 29318394
DOI: 10.1186/s10194-017-0831-1
PMCID: PMC5760492

Genes

HCRTR2
ADH4
CLOCK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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