Article
Molecular analysis of cluster headache.
The Clinical journal of pain - 1 Jan 2015
Zarrilli Federica, Tomaiuolo Rossella, Ceglia Carlo, Lombardo Barbara, Izzo Barbara, Castaldo Giuseppe, Pastore Lucio, De Simone Roberto
Abstract excerpt
OBJECTIVES: Cluster headache (CH) is characterized by severe, recurrent, unilateral attacks of extreme intensity and brief duration. Variants in a myriad of genes were studied in sporadic CH patients, often with conflicting results. METHODS: We studied gene mutations in some candidate genes, hypocretin receptor 2, Clock, and alcohol dehydrogenase 4 (ADH4), in 54 unrelated sporadic CH patients and in 200 controls...
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