Article
Alcohol dehydrogenase 2 genotype and risk for migraine.
Headache - 1 Jan 2010
García-Martín Elena, Martínez Carmen, Serrador Mercedes, Alonso-Navarro Hortensia, Navacerrada Francisco, Agúndez José A G, Jiménez-Jiménez Félix J
Abstract excerpt
BACKGROUND/OBJECTIVES: Alcohol has been traditionally considered a possible migraine trigger factor. Alcohol-dehydrogenase (ADH) enzymes are thought to play important roles in the metabolism of ethanol. Relevant polymorphism has been found only for 2 of the ADH genes (mapped on chromosome ): ADH 1B, betapolypeptide (ADH2) and ADH3. The polymorphism rs1229984, located in the third exon of the human ADH2 gene,...
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