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Article

Genomics and pharmacogenomics of cluster headache: implications for personalized management? A systematic review.

Psychiatric genetics - 1 Feb 2025

Isayeva Ulker, Paribello Pasquale, Ginelli Enrico, Pisanu Claudia, Comai Stefano, Carpiniello Bernardo, Squassina Alessio, Manchia Mirko

Abstract excerpt

The role of genetic factors in cluster headache etiology, suggested by familial and twin studies, remains ill-defined, with the exact pathophysiological mechanisms still largely elusive. This systematic review aims to synthesize current knowledge on cluster headache genetics and explore its implications for personalized treatment and prediction of treatment response. Thus, we searched PubMed, Scopus, and the...

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Genetic Predisposition to Disease
Genome-Wide Association Study
Genomics
Pharmacogenetics
Precision Medicine

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Identifiers

PMID: 39560176
DOI: 10.1097/YPG.0000000000000380
PMCID: PMC11698140

Genes

HCRTR2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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